In the 5th century BC, Kos was taken by the Persians, but after their defeat in mainland Athenian League (479 BC). In 460 BC, Hippocrates, the Father of Medicine, whose name is known throughout the world, since he was the founder of the first school of medicine, was born in Kos. After his death (357 BC), the people of Kos built the famous Asklepeion, in honour of the god Asklepios, which operated as a hospital, admitting thousands of patients from all over the Mediterranean and applying the methods of therapy taught by Hippocrates.